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A carbohydrate-based mechanism of species recognition in sea urchin fertilization BJMBR
Mourão,P.A.S..
In the present review, we describe a systematic study of the sulfated polysaccharides from marine invertebrates, which led to the discovery of a carbohydrate-based mechanism of sperm-egg recognition during sea urchin fertilization. We have described unique polymers present in these organisms, especially sulfated fucose-rich compounds found in the egg jelly coat of sea urchins. The polysaccharides have simple, linear structures consisting of repeating units of oligosaccharides. They differ among the various species of sea urchins in specific patterns of sulfation and/or position of the glycosidic linkage within their repeating units. These polysaccharides show species specificity in inducing the acrosome reaction in sea urchin sperm, providing a clear-cut...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acrosome reaction; Fertilization; Sulfated fucans; Glycosaminoglycans; Sulfated galactans; Species diversity; Sperm-egg recognition.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000100002
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Anticoagulant properties of a crude sulfated polysaccharide from the red marine alga Halymenia floresia (Clemente) C. Agardh - doi: 10.4025/actascibiolsci.v33i3.6402 Biological Sciences
Amorim, Rodrigo César das Neves; Universidade Federal da Amazônia; Rodrigues, José Ariévilo Gurgel; Rede Nordeste de Biotecnologia - RENORBIO; Holanda, Márjory Lima; Universidade Federal do Maranhão; Mourão, Paulo Antônio de Souza; Universidade Federal do Rio de Janeiro; Benevides, Norma Maria Barros; Universidade Federal do Ceará.
Alternative sources of anticoagulants have arisen as a result of the increasing demand for safer anticoagulant clinical therapy, and the sulfated polysaccharides of seaweeds have gained attention in biomedicine. In this study, crude sulfated polysaccharide fractions (denominated Hf1, Hf2 and Hf3) were obtained from the red marine alga Halymenia floresia and the anticoagulant properties of a soluble crude polysaccharide fraction (Hf2s) were assayed. The three differential extractions yielded 38.6%. The polysaccharides are composed mainly of galactose, with small amounts of xylose and glucose. The anticoagulant properties of Hf2s containing 53.8% sulfate and 3% protein was also compared to those of heparin (193.0 IU mg-1) by assays of activated partial...
Tipo: Bioprospecção Palavras-chave: 2.08.01.00-9 Halymeniales; Halymenia floresia; Sulfated galactans; Anticoagulant activity 2.08.01.00-9 Halymeniales; Halymenia floresia; Sulfated galactans; Anticoagulant activity.
Ano: 2011 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6402
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